Jefferson County Courthouse
Jefferson County Courthouse in Monticello

Jefferson County is located in northwest Florida in the panhandle, stretching from the Georgia state line to Apalachee Bay on the Gulf of Mexico. Named for Thomas Jefferson, third President of the United States, Jefferson County was officially formed on January 20, 1827 and now contains 598 square miles of land area and 39 square miles of water surface. The county seat is Monticello.

Jefferson County is traversed east/west by Interstate 10. Part of the St. Marks National Wildife Refuge is in Jefferson County.